Ehrhardt, Anja : rechercher sur Z-Library

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1

Lebenslange Heilung mittels Gentransfer – Realität oder Utopie? Stabiler versus transienter Gentransfer

Prof. Dr. Hans-Joachim Lipps, Prof. Dr. Wolfgang Hammerschmidt, Dr. Anja Ehrhardt

Journal:

Pharmazie in unserer Zeit

Année:

2011

Langue:

german

Fichier:

PDF, 579 KB

german, 2011

2

Viral Hybrid Vectors for Somatic Integration - Are They the Better Solution?

Müther, Nadine, Noske, Nadja, Ehrhardt, Anja

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 678 KB

english, 2009

3

Exploring gene-deleted adenoviral vectors for delivery of short hairpin RNAs and reduction of hepatitis B virus infection in mice

Christina Rauschhuber, Hui Xu, Felix H. Salazar, Patricia L. Marion, Anja Ehrhardt

Journal:

The Journal of Gene Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 706 KB

english, 2008

4

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

Yant, Stephen R., Ehrhardt, Anja, Mikkelsen, Jacob Giehm, Meuse, Leonard, Pham, Thao, Kay, Mark A.

Journal:

Nature Biotechnology

Année:

2002

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2002

5

A rapid protocol for construction and production of high-capacity adenoviral vectors

Jager, Lorenz, Hausl, Martin A, Rauschhuber, Christina, Wolf, Nicola M, Kay, Mark A, Ehrhardt, Anja

Journal:

Nature Protocols

Année:

2009

Langue:

english

Fichier:

PDF, 833 KB

english, 2009

6

Progress and problems with the use of viral vectors for gene therapy

Thomas, Clare E., Ehrhardt, Anja, Kay, Mark A.

Journal:

Nature Reviews Genetics

Année:

2003

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2003

7

Uteroglobin promoter-targeted c-MYC expression in transgenic mice cause hyperplasia of Clara cells and malignant transformation of T-lymphoblasts and tubular epithelial cells

Anke Geick, Peter Redecker, Anja Ehrhardt, Rainer Klocke, Dieter Paul, Roman Halter

Journal:

Transgenic Research

Année:

2001

Langue:

english

Fichier:

PDF, 575 KB

english, 2001

8

New insights into stability of recombinant adenovirus vector genomes in mammalian cells

Christina Rauschhuber, Nadja Noske, Anja Ehrhardt

Journal:

European Journal of Cell Biology

Année:

2012

Langue:

english

Fichier:

PDF, 773 KB

english, 2012

9

Analysis of laser scribes at CIGS thin-film solar cells by localized electrical and optical measurements

Anja Wehrmann, Stefan Puttnins, Lars Hartmann, Martin Ehrhardt, Pierre Lorenz, Klaus Zimmer

Journal:

Optics & Laser Technology

Année:

2012

Langue:

english

Fichier:

PDF, 906 KB

english, 2012

10

Optimization of Cis-Acting Elements for Gene Expression from Nonviral Vectors In Vivo

Ehrhardt, Anja, Peng, Peter D., Xu, Hui, Meuse, Leonard, Kay, Mark A.

Journal:

Human Gene Therapy

Année:

2003

Langue:

english

Fichier:

PDF, 523 KB

english, 2003

11

Laser-induced front side etching of fused silica with XeF excimer laser using thin metal layers

Pierre Lorenz, Martin Ehrhardt, Anja Wehrmann, Klaus Zimmer

Journal:

Applied Surface Science

Année:

2012

Langue:

english

Fichier:

PDF, 332 KB

english, 2012

12

JNK2 Is a Positive Regulator of the cJun Transcription Factor

Anja Jaeschke, Maria Karasarides, Juan-Jose Ventura, Anka Ehrhardt, Chao Zhang, Richard A. Flavell, Kevan M. Shokat, Roger J. Davis

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 734 KB

english, 2006

13

Establishment and characterization of immortal hepatocytes derived from various transgenic mouse lines

Rainer Klocke, M José Gómez-Lechón, Anja Ehrhardt, Tomas Mendoza-Figueroa, M Teresa Donato, Rubén López-Revilla, José V Castell, Dieter Paul

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 412 KB

english, 2002

14

Fabrication of contact holes by rear side laser ablation of polyimide foils for CIGS solar modules

Ehrhardt, Martin, Scheit, Christian, Ragnow, Steffen, Lorenz, Pierre, Wehrmann, Anja, Braun, Alexander, Zimmer, Klaus

Journal:

Applied Surface Science

Année:

2013

Langue:

english

Fichier:

PDF, 651 KB

english, 2013

15

Comparison of Adenoviral and Adeno-Associated Viral Vectors for Pancreatic Gene Delivery In Vivo

Wang, Alfred Y., Peng, Peter D., Ehrhardt, Anja, Storm, Theresa A., Kay, Mark A.

Journal:

Human Gene Therapy

Année:

2004

Langue:

english

Fichier:

PDF, 861 KB

english, 2004

16

Patterning of CIGS thin films induced by rear-side laser ablation of polyimide carrier foil

Ehrhardt, Martin, Wehrmann, Anja, Lorenz, Pierre, Zimmer, Klaus

Journal:

Applied Physics A: Materials Science & Processing

Année:

2013

Langue:

english

Fichier:

PDF, 428 KB

english, 2013

17

Critical Amino Acid Residues Within the ɸC31 Integrase DNA-Binding Domain Affect Recombination Activities in Mammalian Cells

Liesner, Raphael, Zhang, Wenli, Noske, Nadja, Ehrhardt, Anja

Journal:

Human Gene Therapy

Année:

2010

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2010

18

388. Chromosomal Rearrangements in Mammalian Cells Are Induced at High Frequency by the Bacteriophage Derived Integrase phiC31

Ehrhardt, Anja, Engler, Jeffrey A., Xu, Hui, Cherry, Athena, Kay, Mark A.

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 83 KB

english, 2006

19

516. Development of a Minicircle Vector Free of Plasmid Bacterial DNA Sequences and Capable of øC31-Mediated Site-Specific Integration

Chen, Zhi-Ying, He, Cheng-Yi, Ehrhardt, Anja, Xu, Hui, Kay, Mark A.

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 96 KB

english, 2006

20

Somatic Integration From an Adenoviral Hybrid Vector into a Hot Spot in Mouse Liver Results in Persistent Transgene Expression Levels In Vivo

Ehrhardt, Anja, Yant, Stephen R, Giering, Jeffery C, Xu, Hui, Engler, Jeffrey A, Kay, Mark A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 525 KB

english, 2007

21

A Novel Adenoviral Hybrid-vector System Carrying a Plasmid Replicon for Safe and Efficient Cell and Gene Therapeutic Applications

Voigtlander, Richard, Haase, Rudolf, Mück-Hausl, Martin, Zhang, Wenli, Boehme, Philip, Lipps, Hans-Joachim, Schulz, Eric, Baiker, Armin, Ehrhardt, Anja

Journal:

Molecular Therapy — Nucleic Acids

Année:

2013

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2013

22

11. Transposition from a Gene-Deleted Adenoviral Vector Results in Phenotypic Correction in a Canine Model for Hemophilia B

Ehrhardt, Anja, Xu, Hui, Dillow, Aaron M., Yant, Stephen R., Nichols, Timothy C., Kay, Mark A.

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 83 KB

english, 2006

23

Standard Free Droplet Digital Polymerase Chain Reaction as a New Tool for the Quality Control of High-Capacity Adenoviral Vectors in Small-Scale Preparations

Boehme, Philip, Stellberger, Thorsten, Solanki, Manish, Zhang, Wenli, Schulz, Eric, Bergmann, Thorsten, Liu, Jing, Doerner, Johannes, Baiker, Armin E., Ehrhardt, Anja

Journal:

Human Gene Therapy Methods

Année:

2015

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2015

24

Molecular Analysis of Chromosomal Rearrangements in Mammalian Cells After ø C31-Mediated Integration

Ehrhardt, Anja, Engler, Jeffrey A., Xu, Hui, Cherry, Athena M., Kay, Mark A.

Journal:

Human Gene Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 12.75 MB

english, 2006

25

Universal Real-Time PCR for the Detection and Quantification of Adeno-Associated Virus Serotype 2-Derived Inverted Terminal Repeat Sequences

Aurnhammer, Christine, Haase, Maren, Muether, Nadine, Hausl, Martin, Rauschhuber, Christina, Huber, Ingrid, Nitschko, Hans, Busch, Ulrich, Sing, Andreas, Ehrhardt, Anja, Baiker, Armin

Journal:

Human Gene Therapy Methods

Année:

2012

Langue:

english

Fichier:

PDF, 755 KB

english, 2012

26

Adenoviruses Using the Cancer Marker EphA2 as a Receptor In Vitro and In Vivo by Genetic Ligand Insertion into Different Capsid Scaffolds

Behr, Michael, Kaufmann, Johanna K., Ketzer, Patrick, Engelhardt, Sarah, Mück-Häusl, Martin, Okun, Pamela M., Petersen, Gabriele, Neipel, Frank, Hassel, Jessica C., Ehrhardt, Anja, Enk, Alexander H.,

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2014

27

Emerging Adenoviral Vectors for Stable Correction of Genetic Disorders

Lorenz Jager, Bentham Science Publisher, Anja Ehrhardt, Bentham Science Publisher

Journal:

Current Gene Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 291 KB

english, 2007

28

Adenovirus Transduction is Required for the Correction of Diabetes Using Pdx-1 or Neurogenin-3 in the Liver

Wang, Alfred Y, Ehrhardt, Anja, Xu, Hui, Kay, Mark A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 286 KB

english, 2007

29

The Host Response to Adenovirus, Helper-dependent Adenovirus, and Adeno-associated Virus in Mouse Liver

McCaffrey, Anton P, Fawcett, Paul, Nakai, Hiroyuki, McCaffrey, Ramona L, Ehrhardt, Anja, Pham, Thu-Thao T, Pandey, Kusum, Xu, Hui, Feuss, Sally, Storm, Theresa A, Kay, Mark A

Journal:

Molecular Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 396 KB

english, 2008

30

Hyperactive Sleeping Beauty Transposase Enables Persistent Phenotypic Correction in Mice and a Canine Model for Hemophilia B

Hausl, Martin A, Zhang, Wenli, Müther, Nadine, Rauschhuber, Christina, Franck, Helen G, Merricks, Elizabeth P, Nichols, Timothy C, Kay, Mark A, Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2010

Langue:

english

Fichier:

PDF, 529 KB

english, 2010

31

Persistence of High-Capacity Adenoviral Vectors as Replication-Defective Monomeric Genomes In Vitro and in Murine Liver

Jager, Lorenz, Ehrhardt, Anja

Journal:

Human Gene Therapy

Année:

2009

Langue:

english

Fichier:

PDF, 442 KB

english, 2009

32

Involvement of phosphorylated Apis mellifera CREB in gating a honeybee's behavioral response to an external stimulus

Gehring, Katrin B., Heufelder, Karin, Feige, Janina, Bauer, Paul, Dyck, Yan, Ehrhardt, Lea, Kühnemund, Johannes, Bergmann, Anja, Göbel, Josefine, Isecke, Marlene, Eisenhardt, Dorothea

Journal:

Learning & Memory

Année:

2016

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2016

33

Episomal Vectors for Gene Therapy

Ehrhardt, Anja, Haase, Rudolf, Schepers, Aloys, Deutsch, Manuel, Lipps, Hans, Baiker, Armin

Journal:

Current Gene Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 443 KB

english, 2008

34

Conference Report: 17th Annual Meeting of the German Society for Gene Therapy

Büning, Hildegard, Baum, Christopher, Ehrhardt, Anja, Nettelbeck, Dirk M, Ogris, Manfred

Journal:

Therapeutic Delivery

Année:

2011

Langue:

english

Fichier:

PDF, 421 KB

english, 2011

35

Sensitizing ovarian cancer cells to chemotherapy by interfering with pathways that are involved in the formation of cancer stem cells

Saydaminova, Kamola, Strauss, Robert, Xie, Min, Bartek, Jiri, Richter, Maximilian, van Rensburg, Ruan, Drescher, Charles, Ehrhardt, Anja, Ding, Sheng, Lieber, André

Journal:

Cancer Biology & Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2016

36

A High-Capacity Adenoviral Hybrid Vector System Utilizing the Hyperactive Sleeping Beauty Transposase SB100X for Enhanced Integration

Boehme, Philip, Zhang, Wenli, Solanki, Manish, Ehrke-Schulz, Eric, Ehrhardt, Anja

Journal:

Molecular Therapy — Nucleic Acids

Année:

2016

Langue:

english

Fichier:

PDF, 957 KB

english, 2016

37

105. Enhanced Oncolytic Activity Mediated by a Novel Human Adenovirus Type 6 Based Vector

Doerner, Johannes, Zhang, Wenli, Boehme, Philip, Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 332 KB

english, 2016

38

18. Delivery of CRISPR/Cas9 or TALENs Against Hepatitis B Virus cccDNA by High-Capacity Adenoviral Vectors

Schiwon, Maren, Bergmann, Thorsten, Ehrke-Schulz, Eric, Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 295 KB

english, 2016

39

104. A Gene Deleted High Capacity Adenoviral Vector for Efficient Delivery of a Multiplex DMD Specific CRISPR/Cas9 Machinery

Ehrke-Schulz, Eric, Kley, Rudolf A., Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 377 KB

english, 2016

40

106. A Sleeping Beauty Transposase System in the Context of HD-Ad5/35++ Vectors Achieves Stable In Vivo Transduction of Hematopoietic Stem Cells in Mouse Models

Richter, Maximilian, Liu, Jing, Izsvák, Zsuzsanna, Cattaneo, Roberto, Uckert, Wolfgang, Ng, Philip, Ehrhardt, Anja, Papayannopoulou, Thalia, Lieber, André

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 333 KB

english, 2016

41

17. Human Adenovirus D17 Has Tropism for Endothelium Cells and Can Use Both hCAR and CD46 as Receptors

Liu, Jing, Boehme, Philip, Fu, Jun, Zhang, Wenli, Solanki, Manish, Yumul, Roma, Schmidtko, Achim, Stewart, Francis, Lieber, Andre, Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 296 KB

english, 2016

42

103. High-Capacity Adenoviral Vectors (HCAdV) Armed with a High Risk Human Papillomavirus (HPV) Oncogene Specific CRISPR/Cas9 Machinery Specifically Kill Cervical Cancer Cells

Ehrke-Schulz, Eric, Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 337 KB

english, 2016

43

15. A Novel Fast Production Pipeline for High Capacity Adenoviral Vectors to Deliver All Components of CRISPR/Cas9 System for Somatic Gene Editing Using One Single Viral Vector with Multiple Guide RNAs

Ehrke-Schulz, Eric, Leitner, Theo, Dávid, Stephan, Liu, Jing, Schiwon, Maren, Bergmann, Thorsten, Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 297 KB

english, 2016

44

112. A Novel Oncolytic Adenovirus Based on Human Adenovirus Serotype 17

Dörner, Johannes, Zhang, Wenli, Liu, Jing, Solanki, Manish, Boehme, Philip, Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 276 KB

english, 2015

45

194. Adenoviruses Armed with TNFα and IL-2 Successfully Enable Adoptive T-Cell Therapy

Kalervo, Aino, Siurala, Mikko, Havunen, Riikka, Parviainen, Suvi, Bramante, Simona, Saha, Dipongor, Tähtinen, Siri, Vähä-Koskela, Markus, Behr, Michael, Nettelbeck, Dirk, Ehrhardt, Anja, Hemminki, Aks

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 569 KB

english, 2016

46

410. Oncolytic Adenoviruses Armed with TNFa and IL-2 Induce Antitumor Immune Responses and Protection from Tumor Rechallenge

Havunen, Riikka, Siurala, Mikko, Parviainen, Suvi, Behr, Michael, Nettelbeck, Dirk, Ehrhardt, Anja, Hemminki, Akseli

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 298 KB

english, 2016

47

757. Stable In Vivo Transduction of Primitive Hematopoietic Stem Cells After Mobilization and Intravenous Injection of an Integrating Gene Transfer Vector

Richter, Maximilian, Yumul, Roma, Palmer, Donna, Ng, Philip, Izsvák, Zsuzsanna, Cattaneo, Roberto, Liu, Jing, Ehrhardt, Anja, Uckert, Wolfgang, Papayannopoulou, Thalia, Lieber, André

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 325 KB

english, 2016

48

103. Pas de Deux – A Single Inducible High-Capacity Adenoviral Vector for Delivery of a Functional TALEN Pair Directed Against Human Dystrophin for the Treatment of Duchenne Muscular Dystrophy (DMD)

Schulz, Eric, Leitner, Theo, Erdmann-Brendel, Juliane, Bergmann, Thorsten, Gebbing, Maren, Gersbach, Charles A., Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 272 KB

english, 2015

49

669. Standard Free Droplet Digital PCR as a New Tool for More Precise and Reliable Quality Control of Gene Therapy Vectors

Boehme, Philip, Stellberger, Thorsten, Zhang, Wenli, Doerner, Johannes, Jing, Liu, Schulz, Eric, Bergmann, Thorsten, Solanki, Manish, Baiker, Armin, Ehrhardt, Anja

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 365 KB

english, 2015

50

49. In Vivo Gene Therapy of Mobilized Hematopoietic Stem Cells With AD5/35 Vectors Encoding a Sleeping Beauty Transposase Integration Machinery

Richter, Maximilian, Yumul, Roma, Palmer, Donna, Ng, Philip, Papayannopoulou, Thalia, Liu, Jing, Ehrhardt, Anja, Uckert, Wolfgang, Lieber, Andre

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 293 KB

english, 2015